REVIEW ARTIKEL AKTIVITAS ANTIBAKTERI EKSTRAK RIMPANG KUNYIT (Curcuma domestica Val) TERHADAP BEBERAPA SAMPEL BAKTERI

Sheila Meitania Utami, Diah Permata Sari, Nurwulan Adi Ismaya, Erwin Herdiawan

Abstract


The increase in antibiotic resistance is very fast throughout the world, this is a problem because it threatens human health globally. The increase in antibiotic resistance is due to overprescribing of antibiotics, as well as poor infection prevention and control. The use of traditional medicine can be used as an alternative treatment in overcoming health problems, prevention, and healing. Traditional medicine is considered safer than synthetic medicine, one of the plants that has antibacterial benefits is turmeric rhizome (Curcuma domestica Val). Turmeric rhizome has an antibacterial effect against gram negative and gram positive bacteria. This study aims to determine the antibacterial activity and active compounds contained in turmeric rhizome extract that can produce an antibacterial effect. The type of research used is descriptive using the Literature Review method by collecting various sources from 8 research journals that have been published and come from the internet. Turmeric rhizome extract is known to contain curcumin, alkaloids, flavonoids, essential oils, phenols, saponins, tannins, and terpenoids compounds that have antibacterial properties. The results of the literature review of the antibacterial activity test of turmeric rhizome extract showed that the antibacterial activity was classified as moderate to very strong against Escherichia coli (9 mm), Pseudomonas aeroginosa (7,8 mm), Bacillus cereus (11,1 mm), Salmonella typhi (12.1 mm), Staphylococcus aereus (10 mm), and Propionibacterium acnes (20.8 mm), while Bacillus subtilis (1.03 mm) was classified as weak.

Keywords


Active Compound; Antibacterial; Curcuma domestica; Extract Turmeric Rhizome

References


Cahyani, A., Anggraini, D. I., Soleha, T. U., & Tjiptaningrum, A. (2020). Uji Efektivitas Antibakteri Ekstrak Rimpang Kunyit (Curcuma domestica Val.) terhadap Pertumbuhan Propionibacterium acnes In Vitro. Jurnal kesehatan, 11(3), 414-421.

Cobra, L. S., & Amini, H. W. 2019. Skirining Fitokimia Ekstrak Sokhletasi Rimpang Kunyit (Curcuma longa) dengan Pelarut Etanol 96%. Jurnal Ilmiah Kesehatan Karya Putra Bangsa, 1(1), 12-17.

Fikayuniar, L., Gunarti, N. S., & Apriliani, M. 2019. Uji Aktivitas Antibakteri Ekstrak Etanol Rimpang Kunyit (Curcuma longa L.) Terhadap Staphylococcus aureus Dan Pseudomonas aeruginosa. Pharma Xplore: Jurnal Sains dan Ilmu Farmasi, 4(1), 278-287.

Himawan, H. C., Surjana, V., & Prawira, L. 2012. Karakterisasi dan Identifikasi Komponen Kimia Rimpang Kunyit (Curcuma domestica Val.) Sebagai Inhibitor Bakteri Patogen. FITOFARMAKA: Jurnal Ilmiah Farmasi, 2(2), 116-125.

Kumara, I. N. C., Pradnyani, I. G. A. S., & Sidiarta, I. G. A. F. N. (2019). Uji efektivitas ekstrak kunyit (Curcuma longa) terhadap daya hambat pertumbuhan bakteri Streptococcus mutans. Intisari Sains Medis, 10(3).

Lake, W. K., Hamid, I. S., Saputro, A. L., Plumeriastuti, H., Yustinasari, L. R., & Yunita, M. N. 2019. Uji Aktivitas Antibakteri dari Ekstrak N-Heksana dan Kloroform Daun Sirsak (annona muricate I) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Secara In Vitro. Jurnal Medik Veteriner, 2(1), 60-65.

Maulidi, R. R., Ginting, F. BR., Pangaribuan, N. H. D., Sheridan, P. F., & Lubis, Y. E. P. 2020. The Effectiveness Test of Turmeric Extract Toward Bacilus Cereus Bacteria With The Comparison of Ciprofloxacin. Biospecies, 13(1), 15-22.

Muadifah, A., Amini, H. W., Putri, A. E., & Latifah, N. 2019. Aktivitas antibakteri ekstrak rimpang kunyit (Curcuma domestica Val) terhadap bakteri Staphylococcus aureus. Jurnal SainHealth, 3(1), 45-54.

Purwaningsih, N. S., & Apriandini, W. 2020. Uji Efektivitas Antibakteri Dari Ekstrak Daun Kipait (Tithonia diversifolia (Hemsl.) A. Gray) Terhadap Bakteri Propionibacterium acnes. Edu Masda Journal, 4(1), 81-87.

Retnaningsih, A. 2015. Uji Daya Hambat Rimpang Kunyit (Curcuma domestica Val) dan Rimpang Temulawak (Curcuma xanthorriza Roxb) Terhadap Bakteri Salmonella thypi. Jurnal Kesehatan Holistik, 9(3), 158–160.

Rini, C. S., Rohmah, J., & Widyaningrum, L. Y. 2018. Efektivitas Kunyit (Curcuma longa Linn) terhadap Esherichia coli dan Bacillus subtilis. Journal of Medical Laboratory Science/Technology, 1(1), h.1–6.

Sari, A., & Maulidya, A. 2016. Formulasi Sediaan Salep Ekstrak Etanol Rimpang Kunyit (Curcuma longa Linn). Jurnal Penelitian dan Kesehatan, 3(1), h.16–23.

Septiana, E., & Simanjuntak, P. 2015. Aktivitas Antimikroba dan Antioksidan Ekstrak Beberapa Bagian Tanaman Kunyit (Curcuma Longa). Jurnal Fitofarmaka, 5(1), h.31-40.

Suharsanti, R., Astutiningsih, C., & Susilowati, N. D. 2020. Kadar Kurkumin Ekstrak Rimpang Kunyit (Curcuma domestica) Secara Klt Densitometri Dengan Perbedaan Metode Ekstraksi. Jurnal Wiyata, 7(2), h.85–93.

Ulfah, M. 2020. Aktivitas Antibakteri Ekstrak Aseton Rimpang Kunyit (Curcuma domestica) Terhadap Bakteri Staphylococcus aureus dan Escherichia coli. Jurnal Farmasi Muhammadiyah Kuningan, 5(1), h.25–31.

Utami, S. M., & Denanti, I. R. 2020. Uji Efektivitas Antibakteri Sediaan Sabun Cair Cuci Tangan Dari Lendir Lidah Buaya (Aloe barbadensis Miller) Terhadap Eschericia coli dan Staphylococcus aureus. Edu Masda Journal, 2(2), 63-72.

Utami, SM. 2022. Studi Literatur Uji Aktivitas Antibakteri Ekstrak Daun Sirsak (Annona muricata L.) Terhadap Berbagai Sampel Bakteri. PHRASE (Pharmaceutical Science) Journal, 2(1), pp.107-115.

Utami, S. M., Ismaya, N. A., Ratnaningtyas, T. O., & Yunarto, N. 2022. Formulasi Sediaan Minuman Serbuk Fungsional Kombinasi Biji Jagung (Zea mays L.) dan Madu. Jurnal Kefarmasian Indonesia, 109-117.




DOI: http://dx.doi.org/10.52031/phrase.v2i2.415

Refbacks

  • There are currently no refbacks.