FORMULASI DAN EVALUASI AKTIVITAS ANTIOKSIDAN SABUN CAIR BERBAHAN DASAR EKSTRAK DAUN KEMANGI DAN MADU

Bheta Sari Dewi, Sheila Meitania Utami, Ayu Werawati, Wahyu Bachtiar, Agung Dewantoro

Abstract


Basil leaves  (Ocimum sanctum L.) and honey contain flavonoids and polyphenol compounds such as methyl eugenol, which are known to have antioxidant activity. Liquid soap is a form of pharmaceutical product that is often used to cleanse the body and provide additional protection to the skin. Objective: The aim of this study was to obtain the best physical formulation of a liquid soap combination of basil leaf extract and honey and its antioxidant activity. Method: Liquid soap preparations were made by adding basil leaf extract with various concentrations of 2g (FI), 4g (FII) and 8g (FIII) and honey, namely 5g (FI), 5g (FII) and 5g (FIII). Evaluation of liquid soap preparations included organoleptic, pH, and homogenity, as well as antioxidant activity test using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method with a wavelength of 516 nm. Results: The results showed that Formula III (FIII) had the best results, namely organoleptic milk chocolate color, pH preparation (9.71-9.89), homogeneous preparation, stable preparation in storage for 12 days and showed the best IC50 value of 118.39 ppm. Conclusion: In conclusion, the combination of basil leaf extract and honey can be formulated as a liquid soap preparation with a concentration of 8g basil leaf extract and 5g honey in formula III (FIII) showing the effectiveness as the best formulation.


Keywords


basil leaf extract, honey, liquid soap formulation, antioxidants

References


Chandra, B., Rezza, P., Sestry, M., Zikra, A. and Ridho, A., 2019. Phytochemical Screening And Antioxidant Activities Of Kemangi Leaf (Ocimum Tenuiflorum L.) Methanol Extract Using DPPH (1, 1-diphenyl-2-picrylhydrazine) Method. Journal Of Pharmaceutical And Sciences (Jps), 2(2).

Dewi, B.S. and Werawati, A., 2022. Formulasi Dan Evaluasi Fisik Sediaan Serum Anti-Aging Yang Mengandung Ekstrak Tanaman Dari Berbagai Literatur. Koloni, 1(4), pp.789-795.

Dewi, B.S. and Surini, S., 2024. Study on hydrogel eye mask with Centella asiatica L and Aloe vera L extract. Journal of Advanced Pharmacy Education and Research, 14(2-2024), pp.27-34.

Fatonah, N.S., Pertiwi, F.D., Rezaldi, F., Abdilah, N.A. and Fadillah, M.F., 2022. Uji Aktivitas Antibakteri Escherichia Coli Pada Formulasi Sediaan Sabun Cair Mandi Probiotik Dengan Metode Bioteknologi Fermentasi Kombucha Bunga Telang (Clitoria ternatea L). AGRIBIOS, 20(1), pp.27-37.

Gunawan, A., 2021. Penentuan Kadar Fenolik, Flavonoid Dan Aktivitas Antioksidan Maserat Teh Hijau (Camellia Sinensis), Buah Naga Merah (Hylocereus Costaricensis) Dan Jeruk Manis (Citrus Sinensis) (Doctoral Dissertation, Universitas Hasanuddin).

Haerani, A., Chaerunisa, A.Y. and Subarnas, A., 2018. Artikel Tinjauan: Antioksidan Untuk Kulit. Farmaka, 16(2), pp.135-151.

Indriyani, N., Resti Erwiyani, A. and Laila Vifta, R., 2020. Formulasi dan Uji Aktivitas Antibakteri Sabun Cair Ekstrak Terpurifikasi Biji Pinang (Areca catechu L) terhadap Propionibacterium acnes (Doctoral dissertation, Universitas Ngudi Walyo).

Rosmainar, L., 2021. Formulasi Dan Evaluasi Sediaan Sabun Cair Dari Ekstrak Daun Jeruk Purut (Citrus Hystrix) Dan Kopi Robusta (Coffea Canephora) Serta Uji Cemaran Mikroba. Jurnal Kimia Riset, 6(1), p.58.

Sasmita, A.N., Turahman, T. and Harmastuti, N., 2023. Formulasi Dan Uji Aktivitas Antioksidan Sabun Cair Badan Ekstrak Etanol Daun Teh Hijau (Camellia Sinensis L.) Dengan Metode DPPH. Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy, 7(1), pp.1-13.

Saehu, A., Suryani, N. and Noviyanto, F., 2022. Uji Aktivitas Antioksidan dari Formulasi Sabun Mandi Cair Ekstrak Etanol Biji Kopi Robusta (Coffea canephora). Jurnal Biogenerasi, 7(2), pp.124-135.

Sari, F., Kurniaty, I. and Susanty, S., 2021. Aktivitas Antioksidan Ekstrak Daun Jambu Biji (Psidium guajava L) sebagai Zat Tambah Pembuatan Sabun Cair. Jurnal Konversi, 10(1), p.7.

Surahmaida, S. and Umarudin, U., 2019. Studi Fitokimia Ekstrak Daun Kemangi Dan Daun Kumis Kucing Menggunakan Pelarut Metanol. Indonesian Chemistry and Application Journal, 3(1), pp.1-6.

Utami, S.M., Fadhilah, H. and Aprilivani, S.N., 2022. Aktivitas Antioksidan Sediaan Lip Balm yang Mengandung Ekstrak Etanol Buah Labu Kuning (Curcubita moschata D.). Sainstech Farma: Jurnal Ilmu Kefarmasian, 15(2), pp.44-49.

Utami, S.M., Ismaya, N.A., Ratnaningtyas, T.O. and Yunarto, N., 2022. Formulasi Sediaan Minuman Serbuk Fungsional Kombinasi Biji Jagung (Zea mays L.) dan Madu. Jurnal Kefarmasian Indonesia, pp.109-117.




DOI: http://dx.doi.org/10.52031/phrase.v4i2.903

Refbacks

  • There are currently no refbacks.